Nanoparticles Targeting Mast Cells Prevent Allergic Reactions in Mice
Researchers at Northwestern University successfully used a new treatment to prevent anaphylaxis in allergic mice using nanoparticles that targeted the mice' mast cells. These nanoparticles were coated with molecules meant to function as allergens, and another molecule- called Siglec-6 that- that signals mast cells not to react. The result was that the targeted mast cells were deactivated, which protected the mice and kept them from experiencing anaphylaxis. "In one final experiment, mice sensitized to an IgE allergen were given
the nanoparticle infusions with the two antibodies, and exposed to their
allergen. None experienced signs of an allergic reaction."
This is the story of how my son has recovered from an autism spectrum disorder and how I am managing and working to recover from a neuro-immune disease called Myalgic Encephalomyelitis. I discuss the ups and downs of our lives as well as much of the information that led to my son's recovery and my own progress- autism and M.E. are both manifestations of the same underlying disease processes.
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