This blog is a way of sharing the information and resources that have helped me to recover my son Roo from an Autism Spectrum Disorder. What I have learned is to view our symptoms as the results of underlying biological cause, which can be identified and healed. I say "our symptoms" because I also have a neuro-immune disorder called Myalgic Encephalomyelitis.

And, of course, I am not a doctor (although I have been known to impersonate one while doing imaginative play with my son)- this is just our story and information that has been helpful or interesting to us. I hope it is helpful and interesting to you!


Showing posts with label infections. Show all posts
Showing posts with label infections. Show all posts

Tuesday, January 17, 2023

Oral and Dental Health

Is It Possible to Reverse Tooth Decay?
The process of remineralization can be monitored by a dentist with imaging.  This can be helpful because it may not be possible to tell if it is happening otherwise.  

Tooth decay can indicate a nutritional deficiency, such as vitamin D.  Can be done with supplementation.  Foods that provide vitamin D include cod liver oil, liver or desiccated liver pills.  Test again after 3 to 6 months.  Also vitamin K2 (which can also be found in many organ meats).  There are 2 kinds of K2 supplements, MK-4 (animal source, and is more active in the body) and MK-7 (which comes from fermented foods such as natto).  Always supplement vitamin K2 when supplementing vitamin D.  Vitamin A can also be found in cod liver oil.  Taking vitamin D increases the need for vitamin A because they work together.   Magnesium catalyzes all of these nutrients and is needed for vitamin D to work. Magnesium is part of the structure of the calcium phosphate tooth mineral structure.  Magnesium deficiency keeps vitamin D receptors from working.  Fermented foods can replenish oral bacteria which helps teeth regenerate.  The body makes bone by first laying down a collagen matrix, made of amino acids, than calcifies that matrix.  These amino acids are found in bone broth (made from the bones and joints of animals), skin (such as pork rinds), and from supplements. 

How to Treat Cavities and Reverse Tooth Decay Naturally
Some cavities in the teeth can actually be healed and eliminated, and others reduced, by making changes in what you eat.  For a dietary perspective there are 4 causes of tooth decay, which are; excess sugar in the diet, excess phytic acid, not enough minerals, and not enough fat soluble vitamins.  Excess sugar feeds bacteria in and around the teeth causing it to multiply and erode the enamel that is protecting your teeth.  This bacteria can also circulate in your body and lead to cardiac problems and many other health problems.  All refined sugars should be removed from your diet.  At first this should also include natural sugars such as maple syrup and most honey, but these natural sugars may be able to be tolerated somewhat later.  

Phytic acid is a substance found in grains, beans, nuts, and seeds.  Phytic acid binds to minerals in the food and keeps those minerals from being absorbed and used by your body.  Just because a food package says that it contains a certain amount of something, doesn't mean that your body will absorb and be able to use much if any of it.  The phytic acid can be greatly reduced by soaking the food and sprouting it before using it (before milling it into flour in the case of grains.  Personal note- most bean and nut flours are made from beans and nuts that were NOT soaked first).  Make sure to get adequate calcium, magnesium, selenium, iron, phosphorous, silica, and other minerals in your diet.  Vegetables, soaked nuts and seeds, and raw (goat and sheep) dairy are some good sources of minerals.  A multi-mineral supplement can help, and eating a lot of probiotic foods can also help.  

Lastly, the fat soluble vitamins including A, E, D, and K are essential for tooth health.  Vitamins D3 and K2 are essential for our bodies to absorb adequate calcium and to put the calcium in our bones, where it is beneficial, rather than elsewhere in our body (such as our arteries) where it can cause disease.  These can be taken as a supplement and can also be found in raw dairy and fermented foods, such as milk kefir and yogurt.  Getting sunshine on the skin is important as a source of vitamin D.  The fat soluble vitamins are found in fat, such as butter, lard, and some oils, so it is important to eat a good amount of these healthy fats.Vitamin A can be made in your body from beta carotene which is found in orange and green vegetables.  

Another tool for healthy teeth is to do oil pulling, which is an ancient Ayurvedic technique, in which you swish oil around in your mouth.  Use about a tablespoon of oil, coconut and sesame oil (not toasted) work well, and swish it around in your mouth for 5 to 20 minutes.  While swishing it around make sure to "pull" the oil through/between your teeth, and make sure to spit it out when done rather than swallowing it.  You can use the plain oil or add essential oils to it including clove, peppermint, cinnamon, and the best one for dental health is myrrh.  Myrrh can also be rubbed on the gums to treat inflammation.  Additionally a re-mineralizing "toothpaste" can be made by mixing baking soda with a mineral supplement (open the capsule and dump the powder in directly) and optionally an essential oil such as peppermint.  

Dr Axe's guide to oil pulling
Dr Axe's homemade baking soda toothpaste
Dr Axe's homemade toothpaste recipe
More on reversing and healing tooth decay from Dr Axe

Bone Loss Around Your Teeth | The Real Cause Will Shock You | The Side Effects Are DEADLY
Bacterial infections around the base of teeth, at the gumline, can erode bone and gum tissue, which can then compromise the teeth.  These bacteria create biofilm around the roots of teeth.  When a dentist or periodontist probes around the base of the teeth, they are checking to see how deep the "pocket" is between the tooth and the gum tissue around it.  Infections in the gums, called "periodntitis", can then lead to bacteria spreading into the bloodstream.  Once the infection is in the blood it can lead to many serious complications including heart attacks, strokes, angina, and arteriosclerosis.  Additionally, chronic bacterial infection in the mouth can cause very bad breath.  

Another significant source of tooth damage and decay is a misaligned bite.  When the teeth don't line up right during the bite, this causes teeth to move and rock in their sockets, which can loosen them and can make the pockets around the teeth larger thus allowing more bacteria into the gums.  Methods of cleaning teeth at home such as brushing, flossing, using a water pick, etc can't clean deep into the pockets and can't remove the biofilm around the roots of the teeth.  Bacteria can also get into the actual bone structure of the teeth, into little holes called microtubules, which is also out of reach of most methods for cleaning teeth.  These bacteria can reinfect an area around a tooth after it has been cleaned.  These bacterial infections lead to actual bone loss in the teeth.  

Standard teeth scraping and descaling don't address the biofilm and the bacteria beneath the surface.  These techniques are meant to slow down bone loss but not to reverse it.  There is a method of measuring how even the bite is.  The teeth should be sharing the impact 50/50 and the teeth should be meeting in the middle, not on their sides.  Laser therapy can remove the infected tissue, sterilize the roots of the teeth, and can even lead to healing of bone and gums around the teeth.

How To GROW BONE Lost To Gum Disease - AMAZING Results!
There is a method of treating periodontal disease and rebuilding bone around teeth called LANAP, which uses a laser. This method leads to slow regrowth of bone that can take several years to get desired results.  This site has more information about the method and the laser it uses.  

New cavity treatment offers no drilling, no filling
This is new, experimental method of filling teeth with a resin that can be applied to cavities between teeth, and doesn't use the traditional method of drilling and filling cavities.  

!!! Warning about nitrous oxide (laughing gas) that is sometimes used by dentists
Nitrous oxide–induced vitamin B12 deficiency
Nitrous oxide can cause harm due to its "conversion of the active monovalent form of vitamin B12 to its inactive bivalent form ()"

Oil Pulling
Oil pulling is a natural way to treat swollen and receding gums.  Oil pulling means swishing some oil around in the mouth and/or "pulling" it through the teeth.  It can be made with sesame oil (not the toasted kind), which has antibacterial action, or coconut oil.  You can add Triphala Powder (a blend of 3 Ayurvedic herbs including Indian gooseberry, Belleric myrobalan, and Yellow myrobalan) which can prevent bad bacteria from growing in the mouth.  Fennel seeds and cloves are also good and can be chewed.

In one approx. 8 oz jar put 10 to 12 cloves (ground in mortar and pestle, 1/2 tablespoon fennel seeds (ground in mortar and pestle), 1 tablespoon triphala powder, 1/4 cup sesame oil, 1/2 cup coconut oil, close the jar lid and shake well.  Let it sit for 2 days before using, shake it up several times.  Strain the oil into another jar and throw away the leftover sediment.  To use add 1 tablespoon of the oil to 1 tablespoon of water and swish around in mouth for 10 minutes.  Spit it out, do not swallow it. 

Clove Oil For A Toothache or Dental Abscess
An abscess is a fluid-filled cyst.  Clove is anti-fungal (also good to treat candida in the mouth or on the tongue), anti-bacterial, and anti-inflammatory.  It numbs the area in the mouth where it's used so it helps with pain.  You can either chew on a clove directly to release it's oil, or you can put 2 drops in one tsp of coconut oil.  Keep either option in your mouth for 2 to 5 minutes.  Chewing on some garlic has very similar results.  

Supplements and Herbs
Oral Care Extract from Mountain Rose Herbs

Homemade Mouthwash
If toothpaste makes your mouth sore, brush with a solution of 1 teaspoon (5 grams) of salt mixed with 4 cups (1 liter) of water. Pour a small amount into a clean cup to dip your toothbrush into each time you brush.

Rinse your mouth 5 or 6 times a day for 1 to 2 minutes each time. Use one of the following solutions when you rinse:

  • 1 teaspoon (5 grams) of salt in 4 cups (1 liter) of water
  • 1 teaspoon (5 grams) of baking soda in 8 ounces (240 milliliters) of water
  • One half teaspoon (2.5 grams) of salt and 2 tablespoons (30 grams) of baking soda in 4 cups (1 liter) of water  

Wednesday, July 13, 2022

Herpes Viruses in the Brain and Nervous System

Cognitive and psychiatric impairment in herpes simplex virus encephalitis suggest involvement of the amygdalo-frontal pathways
"The long-term neuropsychological and psychiatric sequelae of herpes simplex virus encephalitis (HSVE) and their relationship to the volume of temporal lesions and to amygdala and hippocampus damage remain undefined. We have conducted a prospective study of long-term sequelae in 11 patients with clinically presumed HSVE and detection of HSV DNA in the cerebrospinal fluid by polymerase chain reaction.  Long-term memory disorders were seen in 6 patients, associated with the larger lesions and damage of at least two structures. Long-term behavioural changes with emotionalism, irritability, anxiety or depression were prominent in 7. Left prefrontal hypoperfusion appeared in 8 patients, associated with psychiatric disorders in 7 and left amygdala damage in 6. The reduction of amygdala and hippocampus volume was correlated with the overall volume of lesions. Different patterns of mesial temporal lobe damage occurred, involving either amygdala alone, or amygdala and hippocampus, but never hippocampus alone. MRI volumetric measurements in HSVE could be a good indicator of long-term prognosis. Persistant behavioural changes could be related to an amygdala and frontal dysfunction."

Kluver-Bucy Syndrome is a brain disorder that can occur following a case of Herpes Simplex Virus Encephalitis (HSVE). "The syndrome in humans is due to bilateral destruction of the amygdaloid body and inferior temporal cortex, most commonly due to herpes simplex encephalitis (HSE). It shares visual agnosia and loss of normal fear and anger responses in common with the monkey model but one also sees loss of memory with dementia, distractability and seizures. The hypersexuality tends to be less overt than in the monkeys but may be public and unacceptable."  While the full disorder is rare in humans, apparently partial forms are much more common.  This becomes more relevant when you keep in mind that many human syndromes occur on a very wide scale, so some individuals can have only shadows of the symptoms that are subclinical or only have a few symptoms rather than all of them. 



Saturday, February 10, 2018

Essential Oils

I'm not going to give much background on this topic, since so many people understand it so much better than I do.  I am going to say that from what I understand, quality (and purity) vary a lot between brands so it's worth doing some research into the different brands available to you (and avoiding MLM/pyramid scheme brands including Young Living and DoTERRA.  See this article for links to testing which show fraud on the part of both companies).  The advice that I've gotten from "people in the know" is that with essential oils (EOs) you generally get what you pay for so it may be worth paying a bit more than you otherwise would.  Also, while much of the information available calls for internal use but again the higher quality information sources say to avoid internal use except in certain situations (in which case you should be working with a trained professional), and to always dilute the EO with a carrier oil when using directly on the skin.  Many people trained to use EOs tend to favor using the oils as aromatherapy (inhaled from a diffuser) rather than directly on the body.

Contrary to popular opinion, there actually is some research showing the effectiveness of many EOs as well as how or why they work.  The smell receptors in our noses are the only sensory input organ that sends signals directly into the brain rather than filtering them first, and this is thought to be at least part of why they work.   Essential Oils can be very problematic for people with mast cell disease or other allergic diseases (probably eosinophilic diseases as well), so if you have or suspect you have MCAS please be careful.  Because EOs tend to be very high in salicylates people who do not tolerate them should probably also be cautious.  The following is research that may help us to choose the appropriate oils.

GENERAL
What are the benefits of aromatherapy?
This page from The Mayo Clinic provides a basic introduction to essential oils.
"Essential oils used in aromatherapy are typically extracted from various parts of plants and then distilled. The highly concentrated oils may be inhaled directly or indirectly or applied to the skin through massage, lotions or bath salts.  Aromatherapy is thought to work by stimulating smell receptors in the nose, which then send messages through the nervous system to the limbic system — the part of the brain that controls emotions."

Adverse effects of aromatherapy: a systematic review of case reports and case series
Many fans of essential oils claim that one of their benefits is that they do not and can not cause side effects.  I have never seen anyone try to support this argument, it just seems self-evident to some people.  I don't know how many of the adverse events in this paper were actually caused by essential oils, but I do know that people with MCAS can be very sensitive/allergic to them and that they can bring on many symptoms including life-threatening anaphylactic episodes in some people.  

3 Reasons to Avoid Ingesting Essential Oils
This post challenges the common advice that essential oils are safe to use internally, in particular it points out that just not enough is known about the effects of EOs on the microbiome in the gut.

Essential oils can be safely used on skin when mixed with carrier oils.  A wide selection of very high quality carrier oils can be found hereLotions, aloe vera gel, and witch hazel extract can also be used as carriers.

Why essential oils are not water flavoring agents
This is another post that urges caution about the internal use of EOs, while also discussing some times in which it is appropriate to do so. 

Essential oils of jasmine, peppermint, and rosemary may help reduce stress.

Some EOs have been shown to cause or worsen seizures in some people, and should be avoided by people at risk for seizures. This post lists out which oils these are, and explains why they can be problematic. If you scroll to the bottom of the post, it also has information about which EOs might help with seizures.

ANTIMICROBIAL EFFECTS (emphasis added in quotes below)
Essential oils from aromatic herbs as antimicrobial agents.
"Bacterial resistance to multiple antibiotics is a health problem. Essential oils (EOs) possess antibacterial properties and have been screened as potential sources of novel antimicrobial compounds. Terpenes and terpenoids are components derived from EOs. Some of these EOs show inhibitory activity against Staphylococcus aureus. Carvacrol has specific effects on S. aureus and Staphylococcus epidermidis. Perilla oil suppresses expression of α-toxin, Staphylococcus enterotoxin A and B and toxic shock syndrome toxin. Geraniol shows good activity in modulating drug resistance in several gram-negative species. EOs could act as biopreservatives, reducing or eliminating pathogenic bacteria and increasing the overall quality of animal and vegetable food products. Although clinical studies are scarce, the uses of EOs for topical administration and as penetration enhancers for antiseptics are promising. Little information exists for oral administration."
 
Antibacterial and antifungal properties of essential oils.
"Factors influencing the in vitro antimicrobial activity of essential oils and the mechanisms of essential oils action on microorganisms are reported. This paper gives an overview on the susceptibility of human and food-borne bacteria and fungi towards different essential oils and their constituents. Essential oils of spices and herbs (thyme, origanum, mint, cinnamon, salvia and clove) were found to possess the strongest antimicrobial properties among many tested."

Some Essential Oils Inhibit MRSA, Influenza, and Strep - Scientific Studies
This is a very helpful post on another person's blog that includes a long list of studies and summaries of what the research found.

The inhibition of Candida albicans by selected essential oils and their major components.
"The essential oils of Origanum vulgare, Satureja montana, Mentha piperita, Cinnamomum verum, Cymbopogon flexuosus showed maximum inhibitory activity (MIC = 500 ppm) after 7 days. According to the results of the examination of pure constituents, beta-phellandrene proved to be the most interesting component among cyclic monoterpenic hydrocarbons as it showed a strong activity (MIC = 50 ppm). The most active of phenols was carvacrol (MIC 100 ppm). The open-chain alcohol 1-decanol was the most active of alcohols at 50 ppm. Finally, among aldehydes, a strong activity was shown by trans-cynnamaldehyde (MIC 50 ppm)."

Vapor-phase activities of cinnamon, thyme, and oregano essential oils and key constituents against food borne microorganisms.
"The aim of the study presented here was to gain knowledge about the vapor-phase antimicrobial activity of selected essential oils and their major putatively active constituents against a range of foodborne bacterial and fungal strains. In a first step, the vapor-phase antimicrobial activities of three commercially available essential oils (EOs)-cinnamon (Cinnamomum zeylanicum), thyme (Thymus vulgaris), and oregano (Origanum vulgare)-were evaluated against a wide range of microorganisms, including Gram-negative bacteria (Escherichia coli, Yersinia enterocolitica, Pseudomonas aeruginosa, and Salmonella choleraesuis), Gram-positive bacteria (Listeria monocytogenes, Staphylococcus aureus, Bacillus cereus, and Enterococcus faecalis), molds (Penicillium islandicum and Aspergillus flavus), and a yeast (Candida albicans)".  The results of the study are complex and hard to summarize so please follow the link for more information.

Antifungal activities of essential oils and their constituents from indigenous cinnamon (Cinnamomum osmophloeum) leaves against wood decay fungi.
"The antifungal indices of these two leaf oils at 100 ppm against five strains of white rot fungi and four strains of brown rot fungi were all 100%. Cinnamaldehyde, the major compound in C. osmophloeum leaf essential oils, possessed the strongest antifungal activities compared with the other components. Its antifungal indices against both Coriolus versicolor and Laetiporus sulphureus were 100%. The MIC (minimum inhibitory concentration) of cinnamaldehyde against C. versicolor and L. sulphureus was 50 and 75 ppm, respectively. In addition, comparisons of the antifungal indices of cinnamaldehyde's congeners proved that cinnamaldehyde exhibited the strongest antifungal activities."

Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms.
"The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as the effects of the oils on biofilm formation. For most of the S. aureus (n=6) and S. epidermidis (n=6) strains tested, the biofilm inhibitory concentration (0.125-0.500 %, v/v, for oregano, and 0.031-0.125 %, v/v, for carvacrol and thymol) and biofilm eradication concentration (0.25-1.0 %, v/v, for oregano and 0.125-0.500 %, v/v, for carvacrol and thymol) values were twofold or fourfold greater than the concentration required to inhibit planktonic growth. Subinhibitory concentrations of the oils attenuated biofilm formation of S. aureus and S. epidermidis strains on polystyrene microtitre plates."

Biological and Pharmacological Activities of Carvacrol and Carvacrol Bearing Essential Oils
"Oregano essential oils obtained from the genera Origanum, Thymus, Coridothymus, Thymbra, Satureja and Lippia are rich in carvacrol, a monoterpenic phenol isomeric with thymol... Carvacrol is responsible for the biological activities of oregano. Many diverse activities of carvacrol such as antimicrobial, antitumor, antimutagenic, antigenotoxic, analgesic, antispasmodic, antiinflammatory, angiogenic, antiparasitic, antiplatelet, ACE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities and uses such as feed additive, in honeybee breeding and in gastrointestinal ailments have been shown. This paper highlights these activities and attempts to explain the possible in vivo mechanism of action of carvacrol."

ANTIOXIDANT, PROTECTION, AND DETOXIFICATION PROPERTIES
Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva.
"both lavender and rosemary stimulations decreased cortisol levels. A significant inverse correlation was observed between the FRSA values and the cortisol levels with each concentration of rosemary stimulation. No significant changes were noted in sIgA or alpha-amylase. These findings clarify that lavender and rosemary enhance FRSA and decrease the stress hormone, cortisol, which protects the body from oxidative stress."
"The lemongrass essential oil (LEO) possessed various pharmacological activities, especially the anti-oxidative stress and cancer prevention... However, these effects were suppressed when the cells were also treated with LEO, leading to enhanced levels of SOD and CAT activities (2.9- and 2-fold, respectively, compared with BaP treatment only) and reduced the level of MDA in the cells (43% reduction in malondialdehyde level). At the same time, LEO also reduced the level of DNA damage, as shown by a reduced level of 8-hydroxy-deoxyguanosine (8-OHdG). Taken together, the results showed that LEO offered protection against BaP-induced OS and DNA damage, suggesting that LEO could be a promising agent for lung cancer chemoprevention."

COGNITIVE FUNCTION
Plasma 1,8-cineole correlates with cognitive performance following exposure to rosemary essential oil aroma
https://journals.sagepub.com/doi/full/10.1177/2045125312436573